Critical Issues in Head and Neck Oncology by unknow

Author:unknow
Language: eng
Format: epub
Publisher: Springer International Publishing, Cham

Fig. 9.2Non-cancer death and cancer death survival curves for all trials and for the three groups of trials according to the type of altered fractionated radiotherapy. (a) Hyperfractionation. (b) Accelerated fractionation without total close reduction. (c) Accelerated fractionation with total close reduction. (d) All three groups together. The slopes of the broken lines from year 6 to year ≥ 7 are based on the overall death rates in the seventh and subsequent years. RT radiotherapy

Take Home Message for Altered Fractionation, Part 1

Altered fractionation vs. standard fractionation led to a small but significant absolute OS benefit of 3.4 % at 5 years in patients with LAD HNSCC corresponding to a HR reduction for death of 8 %.

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